I was going to say, same here, I have my spouse, my hobbies, my friends, work I like, what's there to be empty about?
Which country do you live in, by the way?
EDIT: After some light stalking, you aren't in the US. I wonder if life in the US is more alienating, that's certainly what I hear from lots of friends who moved there.
I have the impression that it is, without relying on cold data. I think society is a bit selfish, friendships a bit formal, enthusiasm a bit false and people lack aspirations which aren't career related and life models. But I think these points are valid for the Western hemisphere in general compared to 20 or 30 years ago.
It depends on the country, definitely true for England, maybe true for France, not true for Spain, for example. I think it's mostly northern countries and their colonies. The Mediterranean peoples are very different.
That's been my unscientific observation as well, compared to my stints in other countries. It is the flip side (dark side?) of the highly individualistic culture.
Are you going through a depression?