If shopping I'd compare the highest end Ryzen + motherboard and the lowest end Epyc single socket chip and motherboard and try to guesstimate that price/performance for your workload.
Generally the Threadrippers seem like a much lower volume product and the motherboards are often quite expensive (for the current generation). Both Ryzen and Epyc enjoy significantly higher volumes.
Keep in mind that Threadripper has twice the memory bandwidth of Ryzen, but half the memory bandwidth of Epyc.
If shopping I'd compare the highest end Ryzen + motherboard and the lowest end Epyc single socket chip and motherboard and try to guesstimate that price/performance for your workload.
Generally the Threadrippers seem like a much lower volume product and the motherboards are often quite expensive (for the current generation). Both Ryzen and Epyc enjoy significantly higher volumes.
Keep in mind that Threadripper has twice the memory bandwidth of Ryzen, but half the memory bandwidth of Epyc.