I actually run paint.net inside a windows vbox on OS X. Pixelmator doesn't cut it. People say paint.net is simple but it's actually very powerful. It's just designed so well that it fools people into thinking it's simple.
One downside of pixelmator (as compared to Acorn) - you can't cut/paste Excel spreadsheets and get all the nice formatting and gridlines - Acorn handles that.
Also wondering what is wrong pixelmator. My trial ran out before I could decide whether it was really capable enough. It seemed like something wasn't quite right with it though.