Yes, PRNGs should be good enough, and PRNGs that are supposed to be cryptographically secure should definitely be good enough. (A PRNG that is not cryptographically secure still could be good enough for simulations.) Any method to distinguish a PRNG from true randomness would be the basis of a cryptographic attack on the PRNG. In fact, PRNGs are better for simulations because it allows the results to be reproduced exactly from a small seed.
