You could point out all the lame exploits and bugs, but only if you want to spark a long argument that you will end up losing. There are a variety of things I don't like about Windows, and I avoid using it. But the idea that it's somehow less secure than other operating systems is for the most part a Linux advocacy myth. The fundamental security architecture of WinAPI is just not that different from that of Linux or OS X (which also has a legacy compat issue that complicates its security).
Fair enough, you know much more than me in that domain. :)
Are you going to argue about the famous general instability of Windows compared to its large competitors though? It seems like a good indicator of bad design in low level implementations.
What do you mean by famous general instability of Windows? Windows is perhaps my 3rd choice for OS, but almost all my clients use Windows and among the problems they deal with, instability is not one of them.