On: CSS Equivalent of Prototype?

[mtw]

i use the blueprint framework, which also takes care of typography btw. it's great, well-structured, and I encourage everyone to take a look at it

[mhartl → mtw]

I recently converted my personal site to Blueprint, and found it quite nice. I did have to hack it a bit, but at least it's hackable.

Blueprint is best for layouts with columns of fixed width. For a layout with a variable-width content area, you might want to take a look at http://alistapart.com/articles/holygrail.