It's not clear that you actually watched the video. He's not saying you should never eat fructose. E.g. he points out that fructose is metabolized in a similar way to alcohol with similar bad effects, but he never said "no alcohol" either. The issue he's raising is that Americans have been consuming far too much fructose, and this consumption has been driven by government intervention going back to Nixon.
No, I haven't watched the video, but I've read several of his articles like the one that started this thread (I tend to prefer to read content than watch a video of someone speaking it; quicker to read, less disruptive of people around me, easier to quote, easier to refer back to later to make sure I got his point right, etc; if you have reference to a written description of the same content I'd take a look). Calling fructose a "poison" or "toxin" is excessive. It twists the conventional meaning of those words.
I definitely agree that people are eating too much fructose, and too much sugar in general, and that it has been driven by several government interventions (fat-free diet advice, corn subsidies, etc). I just object to calling it a "toxin" or "poison", and find his single minded obsession with fructose to be a bit of a poor way to attack the problem in the same way that single minded obsessions with "fat free" or "no carb" were. Human diet is a complex topic, with a lot of interacting factors, and over-simplifying advice can be quite harmful.
The main problem for me is the artificial bias the government has induced in our diet through subsidy and taxation. He's fighting against this government interference with our diet, that's a good thing.