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I saw Prof. Stephen O'Rahilly give a talk in 2010 at TEDxCAM.

His research defines a clear link between genetics and obesity, fructose or no fructose. Obviously less intake is better, but many people cannot stop themselves if there is available food. On the other hand, there are people who will stay lean no matter how much food is available.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570383/

Human Obesity: A Heritable Neurobehavioral Disorder That Is Highly Sensitive to Environmental Conditions




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