i'd bet some dollars on dota 2 and tf2 working at near-mouse+keyboard efficiency - those are their main money printing machines right now (...besides the cut sales) and they can't afford to segment their player base by controller, so they must have something in store.
DotA was the main title I was thinking about. If they can make DotA playable with this then I think they are on to something special. DotA is intimidating enough using K+M, if they break down the hotkey barrier with an intuitive controller, they stand to gain a lot.
