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Ilya Grigorik has been advocating using ZeroMQ with SPDY for modern backend RPC.

See "Building a Modern Web Stack"...

AirBnB Tech Talk: https://www.youtube.com/watch?v=ZxfEcqJ4MOM

Slides: http://www.igvita.com/slides/2012/http2-for-fun-and-profit.p...

Blog: http://www.igvita.com/2012/01/18/building-a-modern-web-stack...




BTW: I posted a ticket to add backend SPDY support to App Engine -- see Ilya's comment: https://code.google.com/p/googleappengine/issues/detail?id=9...




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