Our UX team at work uses a Windows-based (e.g., not web-based) wireframe program called Axure[1]. I haven't used it myself, but they seem to be able to produce some pretty good content. They can make custom reusable controls so that the look and feel can be consistent across all our applications.
Of course I'm not a designer so I'm not really qualified to express an opinion beyond the fact that this program exists.
Of course I'm not a designer so I'm not really qualified to express an opinion beyond the fact that this program exists.
[1] http://www.axure.com