Dawkins is not an original researcher. He is wonderful at synthesizing research and writing eloquent popular books.
The importance of The Selfish Gene is to write a correct summary of the neo-Darwinian project. In the future (perhaps even now), it will be more famous for the coining of meme (in an appendix IIRC).
However, The Extended Phenotype is a remarkably original exposition of important (then) contemporary frontiers of Darwinism. It is a powerful idea, powerfully described.
It is certainly his most important original contribution to the literature. And a beautiful book. True and convincing. It will change your view of the world. There is no higher praise.
"The God Virus: How Religion Infects Our Lives and Culture" by Darrel Ray follows in the footsteps of The Selfish Gene to certain logical conclusions about clusters of related memes/concepts (specifically: how religion(s) formed and evolved as clusters of overlapping concepts)
People are generally enthralled by Sapiens which is just a very mediocre extension + shallow interpretation of Dawkins’ thesis.