I'm shooting to do 35mm and medium format. 4x5 is a stretch goal. Even illumination is definitely a challenge, though I use the same technique you do, which is generally refered to as flat field calibration, where we capture the field of light without any target and use it to calculate the offset to apply an even field. One of the trickier aspects is finding affordable lenses with appropriate magnifications that can focus evenly out to the edges of the frame. There are various lenses pulling from scanners or that were specifically used for copying that are useful if you can find them.
