In sticking to vanilla HTML/CSS/Javascript for my hobby projects over the past ten years, I've come to enjoy writing "simple" code with minimal dependencies and bare-bones interfaces. I believe that the skills I've learned in doing so has benefited me many times since then, especially during the times when I needed a specific tool, ASAP, for my job as a biomedical researcher. Without having the need to look up documentation, tease apart the workings of frameworks, I've been able to make hyper-specific web based guis for image labeling and more, sometimes quicker and better than the programmers hired for these jobs, who would otherwise need constant communication and supervision to ensure that the correct thing is built.
