This study would certainly seem to indicate that this is at least true in some form — the study shows that parts of the brain that are typically very well correlated with each other (one fires then the other fires, or they fire together) come uncoupled from each other under the influence of psilocybin.
I'm not sure it could be correctly stated in the gross sense as "jumbling it up and making it re-build," but there certainly is a shift in how the brain's components work together for the duration of the drug's effects, per this study.
I'm not sure it could be correctly stated in the gross sense as "jumbling it up and making it re-build," but there certainly is a shift in how the brain's components work together for the duration of the drug's effects, per this study.