The raise hand feature actually makes these problems worse. There are usually a few more senior and loquacious folks who at some point start to ignore the raised hand queue. They will freely chime in like it's a normal conversation. Once that happens, the raised hand queue is nearly forgotten. This problem is even worse in a mixed meeting when the loquacious folks are all present in the meeting room and the more timid rule-following folks are all remote.
I've been in a couple of meetings like that. Fortunately, the person running the meeting shut down the loquacious people and redirected to the people who followed the rules. That of course was a public reward, so everyone else followed the rules, too. It worked well.