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CAIR2 is specific to California. Every state registry has some technical differences in HL7 V2 Messaging support but most are reasonably close to the CDC/AIRA spec.

https://repository.immregistries.org/resource/hl7-version-2-...

The CDC IZ Gateway can make it somewhat easier to work with multiple state registries.

https://www.cdc.gov/vaccines/programs/iis/iz-gateway/overvie...

In practice the C-CDAs obtained from providers sometimes include immunization section entries so you can pick up some records that way as well




> CAIR2 is specific to California. Every state registry has some technical differences in HL7 V2

Didn't know CAIR2 was only used in CA - I guess a correct statement would be every state has an offshoot of HL7v2, with CAIR2 being one of them, as you mentioned.

> In practice the C-CDAs obtained from providers sometimes include immunization section entries

Yes for sure - we get a lot of those from C-CDAs already, these registries would be just another way to make the data even more authoritative/accurate.




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