It isnt harder than applying one class where you set 15 different things. Only difference is you dont need to spend time naming stuff and you dont need to click to another file to see the styling applied.
There's a massive pile of options for writing styles in the same file as the JS. Naming stuff isn't hard when you use CSS modules. Learning and memorizing the Tailwind DSL takes just as much time as it takes to learn basic CSS.
Do what you want but I honestly don't understand why anyone who already knows how to write CSS would use Tailwind
