Any kind of large-scale change will have some specific people dying compared to the counterfactual of not making the change. To assess whether the change is benign, positive, or negative, we must grapple with both the positive and negative impacts.
For example, I could wave a magic wand today and fix climate change, saving millions or billions of lives. But since I did so, some granny slips on a patch of ice next winter and dies from the fall. Without my magic wand, she would have lived.
Now, I don't specifically know who this granny is before I choose to wave my wand, but as a thinking individual I understand that some such granny must exist. In fact, there are probably many grannies who will die as a result. Would you argue that waving my wand is not a positive change because specific people exist who will be harmed?