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> Frankly the US pays for the cost of the research while the rest of the world just pays for the cost of production.

Top 10 pharma companies, 5/10 are US (2 UK, 2 Swiss, 1 French).

4 of the top 6 for profit margins (from 43%(!) to 19%) are US (Merck is the only outlier, 9th, at 10%).

4 of the top 5 for Sales and Marketing Spend (both on raw dollars and as a percentage of revenue) are US.

3 of the bottom 5 for R&D spend (as a percentage of revenue) are US.

Source: http://www.bbc.com/news/business-28212223




That's a 10 year old article. Although if we rank by market cap top 6 are from the US these days (by revenue 5 out 10 seem to be European) so not much has seemingly changed (besides Novo Nordisk becoming the second most valuable pharma company out of nowhere)


> That's a 10 year old article. Although [the] top 6 are from the US these days […] so not much has seemingly changed

Well, thanks for the update. Correcting a citation an out-of-date article that is - as you admit - apparently still relevant as cited was definitely worth everyone’s time.


The very specific figures from that comment are obviously not really correct. e.g. Pfizer's profit margin in 2023 was ~3.5% which isn't that great (and that's the largest pharma company by revenue).


Keep in mind that marketing is a bit complicated - very few countries allow direct to consumer marketing. I think kits just the US and New Zealand. Obviously there would still be marketing in other countries, but a heavy US presence likely skews things.

https://en.m.wikipedia.org/wiki/Direct-to-consumer_advertisi...


Fun fact: the main reason it was legalized in New Zealand was heavy US pressure and lobbying over trade agreements and there’s been substantial pressure to get rid of it since then.




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