I've moved 22 times in my life. I've never moved from an area due to a single neighbor, but some areas you just feel different than everyone living around you. That causes you (or at least me) to think about moving.
I live in a rural community that is a 20 minute commute from a major research university and another significant college. It's got plenty of "good old boys" as well as others for whom Caroline is basically a bedroom community.
Politics are quite fraught.
Donald Trump is so unpopular in our community that the Republicans have quit running candidates on their own line but instead run independent candidates and even ran a slate in a Democratic primary.
A coworker of mine from years ago has been active in the local Republican Party (successfully ran for town board, lost his race for town supervisor) is one of the leaders of a movement to opposing zoning in our town, something our town board is in the process of implementing. If you counted lawn signs you'd think zoning is unpopular because you see angry NO ZONING signs in front of many of the large properties close to Six-Mile creek where you'd expect Dollar General or another dollhouse village
to come in. They lost their primary and they lost the general election pretty hard so they wound up giving the town board a mandate.
Over time I think the "bedroom community" population is going to increase but it is also possible that national Republicans normalize and their brand becomes less toxic in our town.