No, never been to SF, I have no idea how people drive there or what the conditions are. Except that they're very different from where I drive (except when I'm in the town centre) - roads without sidewalks, mostly no signal lights, snow a large part of the year, and other special conditions.
That is not quite accurate. There are certainly standards for airport markings, but there are many non-standard airports... especially when flying at anything smaller than an international airport.
(And yes, even airliners will sometimes land at small regional airports.)