I agree with that, that they are very different. What I'm saying is, if you're going to start coding for minor audiences – where do you draw the line? And how would you explain to your client/employer that you will take extra care to make sure people with no JS get love but IE6 users get Chrome Frame/redirect?
Where you draw the line isn't just about fractions of the market, though -- it's about market fraction ÷ effort to implement. If there's twice as many IE6 users as no-JS users, but it takes ten times as much work to get your site functioning on IE6 than on a modern browser with no JS, you're better off courting the no-JS segment.
