On: Flipping the model presents a new way to treat sleep apnoea

[xnx]

Reduction is sleep apnea seems like a likely second-order effect of GLP-1 drugs.

[elric → xnx]

Maybe. I'm not convinced. There is some correlation between obesity and sleep apnea, but skinny people can develop sleep apnea just as easily as fat people. It is very difficult to lose weight (and very easy to gain weight) once you do develop sleep apnea for a variety of reasons, so the causal relationship might even be reversed.

That being said, if you suffer from OSA and have a lot of fat on your chest and around your airway, losing some of that fat might help. Maybe GLP-1 drugs can do that in spite of OSA.

[stavros → xnx]

That's a fairly convoluted way of saying "GLP-1 agonists help you lose weight, and losing weight reduces your sleep apnea".

[Maxious → xnx]

We've known since at least 2016 that GLP-1 drugs would have a massive impact https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973216/

[elric → Maxious]

"Massive"? The intervention group went from a mean AHI of 49 to a mean AHI of 37. While the control group went from 49 to 43. It's something, but it's still very much in the "severe" category, and I wouldn't call it "massive".

Proper CPAP usage would reduce this group's AHI to <2 events/hour.

[01100011 → xnx]

Agree, but many of us got sleep apnea while skinny.

Definitely interesting to ponder the far reaching changes of GLP-1 drugs though.