Definitely, but there are a good many people in general that probably consider a small rural town in the middle of nowhere to be a nonstarter in the first place.
I love Marfa, and have visited multiple times. That said, it's definitely a big sacrifice for someone to take a residency there because it's the type of small rural town that doesn't even have a 24 hour pharmacy or proper emergency care without a hour+ drive to a larger nearby town. It's definitely on the fringes of what's acceptable, so much so that it's genuinely surprising when you visit how much of an art enclave it is.