This game is probably one of the best inputs if you want to make estimates about the Drake Equation. Can you really trust every member of every advanced alien species not to hear the siren call of a hypothetical Hypnodrone? One might imagine a galaxy collapsing, the most streamlined self-replicators peeling off "seeds" that start their gravitational brake from ninety-five percent of the speed of light, collapsing the cooler matter of a solar system before waiting to tear apart any local suns and forging enormous linear accelerators so they can begin firing at other unconverted systems in the Orion Arm.
I was under the impression that if there were any aliens in universal paperclips that they were so inconsequential as to be classified as "matter". The adversarial "drifters" are drones from your swarm that have had their values drift since they themselves, of course, are hyper intelligent optimal energy matter converters.