I have both installed and am migrating a game between them now. I don't believe I've actually exported the 4.x version for using the HTML5 profile just yet, so I'll have to give that a go.
It'd be worth your time before you get too deep. The two issues that I ran into:
* CORS issues -- deploying on some sites (esp. gitlab and github pages) runs into issues because of shared buffer requests.
* Assuming you get past the CORS issues, there is still extremely slow load on OSX Chrome -- the app eventually loads, but holy smokes it takes forever.
Both of those nearly made me give up on Godot, but I'm very happy to stay with 3.5.x until those get resolved.
Thanks for the information. I am mostly migrating the game to get a first-hand idea of some of the changes I'm most likely to run into while developing the next one.
I, too, am happy to stay with 3.5.x. It works pretty well for my purposes, though hopefully 4.x will be a viable option for me soon.