It's decent for games on MacOS now too. In particular I was looking at it for playing some FTL mods that are only shipped as windows binaries natively on MacOS a year or two ago (in the end I ended up using Codeweavers Crossover, but I think that the limitations that made me choose Crossover have since been fixed in Wine). I see that a Codeweavers dev is present in this thread (Hi guys, great product, thanks for helping make Wine what it is).
I think that there's still a ways to go for Wine on MacOS at least, like for instance I don't think playing No Man's Sky on MacOS via Wine is viable (or at least it wasn't when I tried a few years ago). I think that's more a limitation of the graphics API MacOS uses though. Supposedly a native port is on the way anyway.