In practice, that difference doesn’t really matter because almost no one is going to store their captured, already-lossy material in a lossless format.
If you know you have to recompress and want to reduce unneccessary artifacts, you do. But beware that uncompressed video in 8 bpc (not HDR) 1080p @ 30 fps is 1,5 Gbps so you'll need 1,3 TB to store your 2-hour capture :)