I actually have this idea where there’s a pedal that shifts your keyboard from qwerty to Dvorak, and some savant can hyper-optimize input by shifting with human look-ahead.
There are plenty of muscles that are underutilised in the computer peripheral world. Feet, legs, toes, tongue, anus. Hardware designers are too orthodox and we're all worse off because of it.
A few years ago I had some pretty bad issues with my hands, mostly caused by using my thumb to reach for the Alt key. My employer bought me some foot pedals that I ended up binding to alt and capslock (since I used my capslock key for ctrl + esc). It actually works pretty great :).