For me, the worst thing is how few comments show up by default in the comments sections. As a moderator of a large subreddit, the new UI is unusable because I can't quickly glance over a massive thread, I'd have to click through to a hundred sub-pages. If they ever remove old.reddit.com, I don't know what I'd do. It's a shame, because the redesign has some actually useful tools that I'd like to be using, but the basic experience is so poor. Every other aspect of the redesign could be fixed in the client with CSS rules, and the slowness and bloat could at least be tolerated.
It's madness. Even old.reddit.com is littered with "load more comments" links that you have to keep clicking through to read. A comments section with 2000 comments should be easy to serve in a single static page. It's just text!