The oleic acid group, the group that didn’t see an increase of metabolites, was given high-oleic sunflower oil. I brought that up because it’s a chemically extracted seed oil, and one of the most common seed oils. “Seed oil” is not a significant distinction of fatty acid composition. Seed oils have varying linoleic acid composition (sesame oil for example is quite balanced, high-oleic sunflower is close to olive oil ratios).
The study you linked showed an increase in oxidation metabolites for the LA group. But as far as I understand, those metabolites don’t demonstrate damage to anything or an impact on mortality. That’s why I linked to a study that measures oxidative DNA damage via 8-oxo-dG in blood, which found no impact from increased linoleic acid consumption. So the theory that linoleic acid is dangerous because of damage via oxidative stress isn’t clearly supported by current literature.
The study you linked showed an increase in oxidation metabolites for the LA group. But as far as I understand, those metabolites don’t demonstrate damage to anything or an impact on mortality. That’s why I linked to a study that measures oxidative DNA damage via 8-oxo-dG in blood, which found no impact from increased linoleic acid consumption. So the theory that linoleic acid is dangerous because of damage via oxidative stress isn’t clearly supported by current literature.