I mean if it is an unrecoverable loss of glial cells during puberty (AFAIK most diagnoses start during that time) then nobody would be able to "flip the bit" back anyway. As glial cells feed and protect neurons, their lack will likely have unrepairable consequences, unless the remaining ones are somewhat boosted to partially cover the functionality of the missing ones. I am interested in this topic because a cousin has inherited it from her father's family (super intelligent people) and their family life is destroyed from it. They basically just manage symptoms with regular crazy periods when one medication ceases to function and they have to switch to another one that might not work.
Most diagnoses for schizophrenia are in the early twenties for men and late twenties for women, so not really in puberty/teenage years. I don't believe anyone can be diagnosed before adulthood if they're not exhibiting exceptionally extreme symptoms either.