> Actually, sickle cell anemia is disproportionately high only in specific populations of black people.
I wouldn't be surprised if we had, by this point, some more specific way of breaking down the susceptible population (other than the gene itself, which we know). It doesn't change the broader point that, breaking things down by "race" alone, we see huge, impactful differences.
Even in drug development, there's a huge push to break down clinical trials by gender and race, because not all drugs work the same in different ethnic populations. By these guidelines, I guess we're not allowed to do that? Race doesn't exist!
When breaking phenomenon down by race it’s important to differentiate phenomenon caused by sociological perceptions of race and actual biological effects of genetic drift, which are distinctly different. I never said race doesn’t exist I merely said it has a poor genetic basis when we can study the actual sub populations of genetic geographic locale. It’s important to test drug trials across different races in the sense that it’s important to try to capture effects across multiple ethnic populations, but in reality race is merely a poor but easy metric to do. Like I said, black people have more genetic diversity than any other race combined. Sub Saharan African has more drift from Aboriginal Australian than White Norwegian, even though the first two groups are both considered black.
To be clear: the sickle cell trait appears elevated in sub-Saharan Africa and descendants from that area. This also means for example black people from Somali aren’t really affected even though Somali is part of the African continent. Does this help clarify my point?
I wouldn't be surprised if we had, by this point, some more specific way of breaking down the susceptible population (other than the gene itself, which we know). It doesn't change the broader point that, breaking things down by "race" alone, we see huge, impactful differences.
Even in drug development, there's a huge push to break down clinical trials by gender and race, because not all drugs work the same in different ethnic populations. By these guidelines, I guess we're not allowed to do that? Race doesn't exist!