Alkyl halides (carbon chains with halogens off of them) can be alkylating agents - basically they can bond to molecules within your body and if it's things like DNA, can cause mutations and other bad stuff.
Nitrogen mustards (highly reactive alkyl halides) are used in chemotherapy. They basically damage DNA which is used to kill off fast reproducing cancer cells (but they also kill off normal cells).
I was a little surprised when I first saw the structure of sucralose. Chlorides aren't that reactive (bromides and iodides are much more reactive), but a person might consume grams of sucralose so concentrations are high.
That said, many experiments have been done and sucralose isn't reactive at all. Due to the shape of the molecule and steric interactions, the chlorines are very difficult to knock off.
Nitrogen mustards (highly reactive alkyl halides) are used in chemotherapy. They basically damage DNA which is used to kill off fast reproducing cancer cells (but they also kill off normal cells).
I was a little surprised when I first saw the structure of sucralose. Chlorides aren't that reactive (bromides and iodides are much more reactive), but a person might consume grams of sucralose so concentrations are high.
That said, many experiments have been done and sucralose isn't reactive at all. Due to the shape of the molecule and steric interactions, the chlorines are very difficult to knock off.
I wouldn't be concerned with taking it.