If by any chance you have not watched "Arcane" I very much recommend it.
Haven't seen much anime apart from the classics (cowboy bebop and the like) and never played League of Legends myself, but found Arcane's whole story, cinematography and action just riveting.
I think it's fair to say it's not anime, but if you were to recommend the show to someone and give a brief description or comparison, I think it definitely shares more stylistic elements with anime than it does with other cartoon media.
Arcane's visuals are indeed stunning, but I strongly disagree about story, mainly because the characters have zero depth.
Vi and Jinx are defined by childhood trauma and little else. Jayce is a charming inventor. Viktor is trying to cure himself. Caitlyn is rich. Etc.
Their origin as video game cardboard cutouts is plain to see. The more interesting ones are originals created for the show (Silco, the cops, a couple others), but they're quickly killed off.
Worst is that all the dramatic moments in the story are triggered by miscommunication between these shallow characters. It's lazy.