This can be the killer app that Deno needs. As of now there is no specific reason for most of the people to try Deno as Node with its plethora of frameworks works and every one can choose their stack as per their taste. But if they can make Fresh sufficiently better (more cohesive and/or performant on both client and server side) and more feature rich on the backend (ORM + Workers/Queuing) with instant deploy then more people might consider switching.
I had no joy trying to get a node JIRA library to run under deno with the various platforms. So still some way to go. Didn't seem far off. IIRC axios was the problem.