If you try simple vanilla javascript, then you may be surprised at how pythonic it is in cerain ways - e.g. just open a browser (any browser!) and you have a javascript REPL read to go in the developer tools.
Node severely complicates and confuses things, but node alone is not javascript. Vanilla JS is IMHO a very nice and expressive language, and you do not need any of the Node/Webpack/React/Vue/jquery/whatever to do effective things in Javascript these days as it is very capable on its own.
I usually do use Vue and Quasar via UMD (?) directly in the browser together with http-vue-loader, which makes it bearable and is pretty powerful as well, but then there's a lot of handpicking with libraries like dayjs (when used with plugins) or TipTap which then just doesn't scale, so you need to start to use some tooling. So you fall back to the recommended tooling and then it begins.
Python is a mess too! There is pip which works great(if you’re lucky), but then the scientific community moves to a different variant of cinda like every two months, which just isn’t necessary usually and way more complicated than just using pip
Oh yeah I personally dislike python a lot because of all the pip and easy_install and anaconda nonsense that exists (existed?). It is a shame that python for some reason became the defacto ML language that people use - I do not really understand how that came to pass (sure there are lots of libraries that help with ML now, but that is a bit of a chicken-and-egg situation)
Try http://deno.land - think of it as sequel to node (written by same guy who created node, aiming to fix mistakes of the past - e.g. deno does not use NPM)
Don't code with JS on the server side at all. There's no real advantage to having JS both on the server and in the client, and there are plenty of alternatives that actually support the features Typescript and the like pretend exist in JS, but really don't.
That sounds like that should have started with "Don't code with Typescript on the server side at all" instead. If Typescript is pretending things unsuccessfully, you might as well stick with plain Javascript. (It wouldn't surprise me if Javascript ultimately lived longer, just like Smalltalk actually outlived Strongtalk in the end.)
Deno, as someone mentioned. Also, Civetweb embeds Duktape. Also, txiki.js embeds QuickJS. So there's at least three other options with varying features. You should try Deno first, though.
Node severely complicates and confuses things, but node alone is not javascript. Vanilla JS is IMHO a very nice and expressive language, and you do not need any of the Node/Webpack/React/Vue/jquery/whatever to do effective things in Javascript these days as it is very capable on its own.