From what I recall reading about epigenetics, diabetes is caused by a too fast change in diet towards high calorie. After several generations the metabolism thriftiness goes down if the diet level remain the same, and thus diabetes rates will go down. Same concept happens in reverse when there is periods of famine.
Type 1 diabetes is an auto immune disease that destroys your pancreas.
Type 2 diabetes is an acquired and reversible disease that follows insulin resistance and it is caused by excessive amounts of glucose in your blood, which forces your pancreas to release an ever increasing amount of insulin which then is absorbed by fat cells until they hit insulin resistance, then it fills up muscle cells including your heart until they hit insulin resistance until the only place left for the glucose is inside your organs.
The easiest way to reverse diabetes or avoid heart surgery is to get a live glucose monitor and then do a ketogenic diet. It's non invasive and if done correctly is more effective than any surgery can ever hope to be.
As my endocrinologist put it, diabetes is a disease about decision making.
Right now, there’s little evidence that a CGM actually helps Type 2 patients make better decisions. More information doesn’t lead to better decision making. Better decision making processes and changes to lifestyle lead to better decision making.
From 2020:
“Although continuous glucose monitoring may benefit patients with type 1 diabetes mellitus, there is limited evidence that it offers similar benefits in patients with type 2 diabetes, regardless of whether they are taking insulin.”
“Until we have research supporting continuous glucose monitoring for patients with type 2 diabetes, especially those not receiving regular insulin injections, there are no patient-oriented benefits to justify its great expense and additional hassles for patients and physicians.”
My guess is that I read it in a book by Robert Sapolsky titled Why Zebras Don't Get Ulcers, but I won't reread the book just to give you the exact page number. It could also be one of the youtube talks by him where he go through epigenetics.
To quote the later study: "Given that risk for diabetes and its complications is linked to both genetic and environmental factors, it is not surprising that there are now more than 1,000 articles that address the intersection of diabetes and epigenetics or epigenomics"
The case study that I remember was studies done on Indigenous populations when they got introduced to a west-style diet by being integrated into west society. The following generations had higher rate of type 2 diabetes compared to children of existing demographics. There has also been a plentora of studies done on children born after the dutch hunger winter (https://en.wikipedia.org/wiki/Transgenerational_epigenetic_i...), where one of the finding was increased risk of glucose intolerance in adulthood.
