Just a note: Neither Ghostery or Disconnect work in Chrome, since Chrome doesn't have any kind of ability to block requests from being made. The experimental webRequest API should help with that, but it hasn't been released yet.
can you clarify? both ghostery and disconnect do install and run in chrome - i have them running now. are you saying that there is some particular functionality that they don't provide?
also, responding to the (grand) parent, someone else mentioned that flash cookies are cross-browser. so if fb uses those you need to also make sure that the fb browser doesn't have flash installed.
They both install and run, but they use beforeRequest and edit the page content. This works in theory, but in practice there is no guarantee that the script will be loaded into the page before the tracker assets are. The ghostery/disconnect addons succeed in blocking trackers sometimes, but not all. Ghostery handles it a bit better than Disconnect does, as it will actually tell you which trackers it was able to block and which it wasn't.
The experimental webRequest API will solve that by providing a synchronous way for scripts to deny/allow connections before any requests are made, but webRequest won't be made available to non-experimental addons for a few months at the minimum.