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Good question, if I am correct there is also a higher chance to develop MS if you are a woman and if you live in the northern hemisphere and some parts of Australia and New Zealand.

Also if you are of Northern European descent the risk is higher if I remember correctly.

Possibly it's a mix of many things and you have to be one of the unlucky people where that mix triggers something in the immune system and the disease develops.

I am very unlucky in that regard.

According to my doctors the number of autoimmune diseases I have is rare in a single person.

I have a sysmetic autoimmune disease (Rheumatoid Artritis) and autoimmune diseases in my kidneys, liver,thyroid, skin and mouth.

So somehow multipe times there were events in my life where a mix of things caused my immune system to turn against me.

A little off-topic, but to give an impression of how that works out in daily life, in case you are also diagnosed with an autoimmune disease.

If you are lucky, there is good medication and you will hardly notice you're ill, except for the checkups with your doctor

I also know some autoimmune diseases can (become) pretty aggressive, but n=1, most people I know with autoimmune diseases have a decent quality of life.

Fortunately, in my case also for each disease there is medication that either supresses the inflammation or the protects my body against the effects of the auto-immune response.

So I take my pills and a bi-weekly injection with a biological and I can continue to live with a decent quality of life.

Except for one important thing, my main remaining symptom is that I have a lot less energy than most people and need much more sleep.

Despite that all inflammation parameters in my blood show no signs of inflammation or activity of the disease, my body somehow loses energy to something.

This seems to be a complaint of many autoimmune illness sufferers, no signs of activity of the ilness, but more tired than before the disease came into their life.

Hopefully there will soon be more developments in this area of medicine.




> if I am correct there is also a higher chance to develop MS if you are a woman and if you live in the northern hemisphere and some parts of Australia and New Zealand. Also if you are of Northern European descent the risk is higher if I remember correctly.

I believe this has been largely disregarded. The higher incidence rate in Europe/Anglosphere was a consequence of higher testing and accurate diagnoses, coupled with the ability to provide treatment.


Yes, inflammatory signals can and do pull metabolic levers, something that is criminally under appreciated, and this can manifest as feeling tired somehow. There is absolutely a connection.




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