there is an experimental[0] treatment for MS, the "immune system reboot". i am a layperson but my understanding is stem cells are taken from the patient, the immune system is "destroyed" through immunosuppressants and the stem cells are then used to rebuild a "naive" immune system in the patient.
based on the info in the OP, i wonder if the MS result from EBV is random; what is the probability of a rebooted immune system to follow the same path after exposure?
The initial susceptibility is mostly going to be predetermined by the MHC, and therefore remain the mostly the same. However, the pathological outcome is ostensibly a product of certain strains of pathogens plus luck of the draw on somatic hypermutation in response to said pathogen.
based on the info in the OP, i wonder if the MS result from EBV is random; what is the probability of a rebooted immune system to follow the same path after exposure?
[0] - https://www.nih.gov/news-events/nih-research-matters/immune-...