It's more something you'd do at boot, if you had to select between an OS built for one or another.
The POWER ISA was used in PowerPC which was used for the successors of a few 68k machines (most famously the Macintosh) and in that case the OS was built for big-endian. So having big-endian support was key there.
IBM i and AIX still run big, in fact. Important for IBM's institutional customers.
As for endian shifts, technically every OpenPOWER chip goes big for every OPAL call into the low-level HAL, even if the OS is little. The overhead is minimal. I can't think of much application use for that, though (per-page endianness which some PowerPCs supported is much more useful).
The POWER ISA was used in PowerPC which was used for the successors of a few 68k machines (most famously the Macintosh) and in that case the OS was built for big-endian. So having big-endian support was key there.