If the system can change the endianess at any time, does that mean that we should only be using palindromic data? Or is it that we should aim to make everything polyglotic such that both directions have valid but distinct interpretations?
you joke but I learned at a talk comparing genetics to TCP networking (at HOPE, maybe 2014 or 2016, cant find it on the website atm) that DNA is encoded such that it expresses different proteins depending on which direction it is read, might be something to learn from
;)