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Maybe? But there are cases where the answer is either "no" or "it's too expensive." I've interacted with people with very serious mental disabilities and while it's not necessarily a negative experience you can usually tell the parents are lying to themselves when they say they enjoy their life.

If you create a hypothetical where the outcome is bad then I am not surprised the outcome is bad. You need to find something more concrete. I actually gave one: selecting against something nebulous like depression may have deleterious effects on the human germline leading to our own extinction. There's evidence that depression aids in avoiding potentially deadly stressors and increases problem solving ability.




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