.bashrc runs tmux for me automatically but only if I ssh in. It removed just enough friction from using tmux that I finally put in the time to learn it. Would recommend/10
I would say having the exact same keyboard shortcuts for interacting with windows, panes, etc for both your desktop as well as any other machine you work with is worthwile having.
https://stackoverflow.com/questions/27613209/how-to-automati...