There are quite a few nucleoside analogues that have been used for HIV treatment: AZT, Zerit, FTC, Videx, Abacavir, 3TC, Hivid. There may be others I'm missing.
Of these, only Abacavir and FTC (as part of Truvada) are still used, the others have fallen out of use or are no longer even manufactured due to their bad side effect profiles and propensity for severe adverse reactions. 'Nuke-sparing' regimen planning specifically would combine other classes of drugs to avoid this class due to side effect issues.
I think it's great to have this new treatment option but this class of medications is well known for its side effects. Avoiding vaccines as 'unproven' and then going for this in particular I would consider eye rollingly wrong headed.
Of these, only Abacavir and FTC (as part of Truvada) are still used, the others have fallen out of use or are no longer even manufactured due to their bad side effect profiles and propensity for severe adverse reactions. 'Nuke-sparing' regimen planning specifically would combine other classes of drugs to avoid this class due to side effect issues.
I think it's great to have this new treatment option but this class of medications is well known for its side effects. Avoiding vaccines as 'unproven' and then going for this in particular I would consider eye rollingly wrong headed.