No problems whatsoever with Ubuntu based distros (like Mint) with Nvidia whatsoever. If you want to install the newest Mesa from a PPA, one of them has instructions for Mint. I'd recommend openSUSE over Fedora, less Gnome focused, more pragmatic than laboratory to push the boundaries and rolling release in case of Tumbleweed. Instructions for Nvidia drivers are here [0]. Just saw a guide to Setting up MicroOS as a desktop OS (their equivalent to Fedora Silverblue, immutable OS). Might try that one on the machine i still have to migrate from a Cinnamon/KDE-FrankenMint to Tumbleweed.
[0] https://opensuse.github.io/openSUSE-docs-revamped-temp/insta...