Some of those weights presumably go to reproducing highly-conserved features, like the kinetics of particular ion channels. These are "tied" via the genome, in the sense that there's one KCNC1 gene, but millions of neurons express the ion channel it encodes.
On the other hand, this model is also missing all sorts of other interactions: hormones and other neuromodulators, ephaptic coupling, etc.
It's so complicated I would venture that no one even has a reasonable guesstimate of how close we are, beyond "Not very."
Some of those weights presumably go to reproducing highly-conserved features, like the kinetics of particular ion channels. These are "tied" via the genome, in the sense that there's one KCNC1 gene, but millions of neurons express the ion channel it encodes.
On the other hand, this model is also missing all sorts of other interactions: hormones and other neuromodulators, ephaptic coupling, etc.
It's so complicated I would venture that no one even has a reasonable guesstimate of how close we are, beyond "Not very."