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I was asking more in the general case for coffee.

I mean, I know basically how many beers will get me drunk and am well aware of the times I drink. Coffee, though? I read tons of folks saying it affects them... But it feels similar to the folks saying vitamin d improved their life. I am not claiming they are false, but I am claiming I don't feel it.




I don't have a source for this, but I've heard that coffee legitimately does affect some people differently. Because some people have a gene for an enzyme that metabolizes caffeine very effectively, and others don't.

Which, that may not even be true. In which case, I don't mind. It was all by way of illustrating, be careful trying to extrapolate from a sample size of 1. In fact, just don't do it. Conversely, don't assume an aggregate statistic accurately describes anybody in particular.


Would love to read a bit more on that. If anyone has a good source on variation of caffeine susceptibility, I'd be grateful!

And the point on being careful extrapolating makes sense. I will work on that.


This will interest you "Interindividual Differences in Caffeine Metabolism and Factors Driving Caffeine Consumption" : https://pharmrev.aspetjournals.org/content/70/2/384


It's hard to tell without knowing of strong your coffee is, your pink grapefruit intake and most importantly your sensitivity to caffeine.


This feels like I'm getting phished. :) Pink grapefruit intake? Awfully specific.

Coffee is as strong as I can find. I prefer the taste of robusta beans. Have taken to steamed milk lately, but no sugar.

I'll check out the link you put in the other post. Thanks!


I don't know about grapefruit and caffeine specifically, but it's at least a great example from a tongue-in-cheek perspective. Grapefruit has a kind of ridiculously long list of drug interactions. It seems like pretty much everyone I know over the age of 65 is under doctor's orders to stay away from it.

https://www.fda.gov/consumers/consumer-updates/grapefruit-ju...




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